Objective To review the advances on lovastatin fermentation by Aspergillus terrus.

目的綜述土曲霉洛伐他汀發(fā)酵研究的進展.

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Objective To construct one of yield lovastatin strain that is a very valid medicine for cholesterol - lowering.

目的探索構建洛伐他汀高產菌株的原生質體制備和融合方法.

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Methods: Simvastatin was synthesized from lovastatin via acetylization, methylation, hydrolytic decomposition and cyclization reactions.

方法: 以洛伐他汀為原料,通過?；?、 甲基化 、 水解、環(huán)合等反應合成了辛伐他汀.

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